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ARB (Blood Pressure)

Losartan

Also sold as Cozaar

Mild zinc influence; generally well tolerated.

This page provides educational information about possible medication-related nutrient relationships. It does not diagnose a deficiency, establish that this medication caused a symptom, or replace qualified medical care.
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Overview

About Losartan

Losartan belongs to the ARB (Blood Pressure) class. Recognized brand names include Cozaar.

Mild zinc influence; generally well tolerated.

MyDeficiencies does not provide dosing instructions, adverse-effect lists, or personalized medical advice. Always follow the guidance of your prescribing clinician and pharmacist.

Nutrient relationships

Possible Nutrient Relationships

  • Zinc

    Emerging Evidence

    Immunity and antioxidant defense.

    Available evidence suggests Losartan may affect zinc status. Individual responses vary.

How to read this page

Evidence Strength

Evidence labels reflect the current strength of available research, not a guarantee of individual outcomes:

  • Stronger Evidence — Consistent, replicated evidence across multiple well-designed studies.
  • Moderate Evidence — Supportive evidence with some variability across populations or study designs.
  • Emerging Evidence — Early or mechanistic signals that warrant continued study.

Read our full evidence framework →

Proposed mechanisms

How These Relationships May Occur

Selectively blocks angiotensin II AT1 receptors; mild influence on trace mineral balance.

A proposed mechanism explains how a relationship might occur. It does not prove that a clinically meaningful deficiency occurs in every individual.

Combinations reviewed

Reviewed Combinations

  • Losartan + Lisinopril

    Stronger Evidence

    Dual RAAS blockade — ACE inhibitor + ARB acting on the same pathway.

    Significant risk of hyperkalemia, hypotension, and acute kidney injury. Typically contraindicated.

For your next visit

Questions You May Want to Discuss

  • Could Losartan affect any nutrients over time in my situation?
  • Are there symptoms or risk factors that would make further evaluation appropriate?
  • Could diet, other medications, or health conditions affect this relationship?
  • Would laboratory testing be clinically appropriate for me?
  • Are there medication or supplement interactions I should understand?

These are conversation starters, not recommendations to request a specific test, supplement, or medication change.

Research

Research and Sources

Formal citations for Losartan are being catalogued. See our Research Center for evidence standards and methodology.

See our evidence methodology for how sources are evaluated.

View MyDeficiencies research updates(research revisions are tracked centrally, including for Losartan)
Related nutrients

Related Nutrients

  • Zinc
    Emerging Evidence
Ready to go deeper

Explore Losartan in Your Report

Add Losartan to a MyDeficiencies analysis to view its reviewed nutrient relationships alongside other medications, supplements, symptoms, and relevant context.

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Educational only. Not a diagnosis. Not a substitute for qualified medical care.